The principles of inclusive education, developed in the twenty-first century as the principles of equal and universal access to quality education taking into account the special educational needs of individual, necessitate a significant transformation of educational programes, in particular, in the system of higher education. Noting the importance of substantive aspects of education, the authors focus on the implementation of blended learning models in the framework of the programme "Affordable educational environment" in Russia. The development of modern information and communication technologies has become a prerequisite for widespread use of technologies and e-learning at the Kazan (Volga) Federal University. E-learning at KFU consists of the learning management system, Portal of e-learning, software and hardware and software solutions, training and methodological support for authors of e-courses, and for students to work in the learning management system. It is in the form of manuals, methodical recommendations, instructions, training e-courses. General information about e-learning in KFU and some results of its using in the inclusive education are described in the article.