Preventing students with visual impairment (SVI) from participating in Science and Mathematics lessons is denying them the opportunity of equal educational opportunity promised by the Federal Government of Nigeria. It is against the Education for all Acts (1990) and No child left behind act (2002) which Nigeria is a signatory. Denying SVI this opportunity put them at a risk of lonely, isolated and unproductive lives (Texas school for the blind and visually impaired). Not only is the possibility of producing future scientist who have impaired vision but the contribution of science in making the blind or visually impaired live a fulfilled life cannot be overstressed. To John Gardener, a blind Physicist it is an awful thing to do to a kid, just wave a course because he cannot learn it. This paper showcase inspirations from scientists who are blind or visually impaired, their contributions in the field and specific techniques used that enabled them to do science are reviewed to serve as direction for Nigeria. For instance, Supalo, a professor of Chemistry employ paid readers to draw responses on all assessment, emphasise the need to develop habit of thinking creatively, know what adaptive technology is available and be good in problem solving skills. Gary Vermeiji said the prevailing attitudes about science and the blind must be reformed. Scientifically inclined blind should not be steered toward the social sciences away from fields in which laboratory and outdoor studies are important. He believes the chief factor holding the blind back from science is ignorance.